Q.1
The main neuroreceptors involved in emetic response are:
Epinephrine and norepinephrine
Serotonin and dopamine
Cholinesterase and prostaglandins
GABA (gamma-aminobutyric acid)
Q.2
Which of these patient populations is NOT considered high risk for chemotherapy-induced nausea and vomiting?
22-year-old patient
Female patient
Breast cancer patient
Geriatric patient
Q.3
A patient asks a nurse, “Isn’t there one drug that can prevent both acute and delayed nausea?” Which is the best response provided by the nurse?
No drug has been developed that can treat both types of nausea due to physiological mechanisms involved within the brain
Promethazine and haloperidol are effective in treating all types of nausea and vomiting if started early in the chemotherapy regimen
NEPA (a combination of netupitant and palonosetron), is used to treat acute and delayed nausea
Any drug that crosses the blood brain barrier is typically not useful in treating nausea but can inhibit vomiting
Q.4
Which neurokinin-1 receptor antagonist has the longest half-life (duration of action)?
Netupitant
Aprepitant
Rolapitant
Fosaprepitant
They are all about the same
Q.5
When providing a patient with education on side effects of aprepitant, a nurse should include which of the following common adverse effects?
Peripheral neuropathy, sedation, and tinnitus
Tiredness, hiccups, and constipation
Brittle nails, sinusitis, and heart palpitations
Muscle weakness, urinary retention, and ataxia